The concept of stress is as elusive as it is important. Stress is ubiquitous. No person escapes of some sort or the other in daily life. In this sense people are seen as passive helpless victims of the stress phenomenon. In a sense it is a new generic term for 'cause- effect' relationships.
The aim of every human being is to survive as happily as possible. In an ever changing world and to achieve the highest possible consistent with one's potentialities. It is the gap between achievement and expectation that leads to stress. For the present concept of stress we owe a great deal to the pioneering work of Prof. Hans Selye, who was awarded the Nobel Prize for this work.
What is Stress ?
(a) Definition: Stress is now formalized to mean - any change within a system induced by external forces. Stress is a demand on our adaptability to evoke a response. In a fast changing world the demands on human adaptability are great and hence, chances of stress being produced are greatly enhanced.
(b) Selye's Concept: Prof. Selye noted that animals exposed to a wide variety of noxious agents, underwent a somewhat 'stereotypic pattern' of physiological changes. In this sense they were 'non-specific'. He designated this response pattern as 'General Adaptation Syndrome'(GAS) and the stimuli that provoke the syndrome were called 'stresses' or 'stressors'. Derailment of GAS produces 'diseases of adaptation'. In GAS the bodily physiological responses evolve in three stages:
(a) The 'alarm reaction' (b) The 'stage of resistance' (c) The 'stage of exhaustion' - implies a decline of defence reactions.
It would be borne in mind that the outcome of GAS is to some extent influenced by the specific nature of the demanding agent.In addition certain factors not connected with stress modify the pattern of GAS. Such factors are: heredity. diet. pre-existing disease of certain organ systems etc. These are called 'conditioning factors'.
The Defence against stress occurs in two phases. Initially the stressor evokes by way of the hypothalamus a strong 'sympatho- adrenal discharge'. The release of stored catecholamines produces their characteristic cardio vascular and metabolic reactions e.g. rapid heart rate, raise in blood pressure, increase in blood sugar level etc. If the stress is not severe or is of short duration this may restore to normality.
If the stress is sever and long lasting additional defence reactions are called into play. There is release of cortico-steroids from the adrenal cortex, mediated through the hypothalamus, leading to increased liberation of ACTH and a shift in the balance of pituitary hormones. It is now believed that besides the hypothalamus the limbic and reticular system also come into play to organize the resistive response.
Thus, there is a psychic and emotional contribution in the initiations to stress response and consequent compensatory adjustments. The automatic nervous system (ANS) also plays an important part in expression of emotion as evidenced by blanching or flushing of the skin, cardiae acceleration, pupillary dilation, pilo-erection, sweating etc.
To summarize then it may be said that 'stress' acts on the organism - producing GAS - which acts on the 'Target Organ'. If the stress is long lasting or severe, adaptation is derailed and psychic or somatic disease results.
Conditioning factors modify the stress response. Two important contributions accrue from Selye's work. (a) The understanding of mechanism of stress and that of the defence to stress is through the Nervous mechanism and Hormonal defence. Conditioning factors also determine the outcome of stress. (b) There exist a large number of diseases whose causation we do not comprehend or comprehend but dimly. These are what Selye likes to call 'Disease of Adaptation' and may include disorders of psycho-somatic origin. The list is polymorphic. To quote a few: ulcerative colitis, peptic ulcer, rheumatic disease, hypertension, asthma, arthritis, cardiac disorders, neurosis, depression etc. may be produced by maladaptation.
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